| Carol Seiple | Basketball | 1943 | |
| Larry Willey | Basketball | 1956 | U. of Cincinnati |
| Jim Myers | Basketball | 1962 | U. of Michigan |
| Jay Lehman | Basketball | 1977 | U. of Toledo |
| Kirk Lehman | Basketball | 1978 | Ohio University |
| Greg Kampe | Basketball | 1974 | Bowling Green |
| Mark Hetz | Basketball | 1975 | Ohio State |
| Kristen Grant | Basketball | 1988 | Cleveland State |
| Scott Taylor | Baseball | 1988 | Boston Red Sox |
| Andy Smith | Baseball | 1993 | Bowling Green |
| Mark Franz | Baseball | 2000 | Ball State |
| Christian Snavely | Baseball | 2000 | Ohio State |
| Luke Hagerty | Baseball | 2002 | Chicago Cubs |
| Chad Billingsley | Baseball | 2001/02/03 | L.A. Dodgers |
| John Niese | Baseball | 2004/05 | N.Y. Mets |
| Tyler Burgoon | Baseball | 2007 | U. of Michigan |
| Cameron Stykemain | Baseball | 2007 | Niagara U. |
| Adam Wagner | Baseball | 2008 | Niagara U. |
| Dace Kime | Baseball | 2008 | U. Of Louisville |
| Dace Kime | Baseball | 2009 | U. Of Louisville |
| Craig Gutman | Baseball | 2009 | |
| Alex Nofziger | Baseball | 2009 | |
| Dace Kime | Baseball | 2010 | U. Of Louisville |
| Anthony Kidston | Baseball | 2011/12 | U. Of Louisville |
| Robert Zeigler | Baseball | 2012/13 | Kentucky |
| Weston Rivers | Baseball | 2013 | Lincoln Trail |
| Jim Windnagel | C.C. | 1975/76 | 9th/3rd U. Toledo |
| Chip Shank | C.C. | 1977 | - |
| Kwasi Diehl | C.C. | 1979 | - |
| Kellan Stephans | C.C. | 2000 | - |
| Patrick Mouser | C.C. | 2000/01 | 4th/4th Auburn U. |
| Darren Flickenger | C.C. | 2004 | U. Toledo |
| Kristen Barth | C.C. | 2004 | - |
| Lauren Fett | C.C. | 2006 | - |
| Zack Wiles | C.C. | 2007/08 | 9th/8th Boise St. |
| Lauren Fett | C.C. | 2007 | Ohio University |
| Trevin Flickenger | C.C. | 2008/09 | 10th/8th U. Toledo |
| Abel Flores | C.C. | 2009/10/12 | 6th/2nd/2nd E. Michigan |
| Alex Barrientos | C.C. | 2012 | 11th |
| Nate Wichman | C.C. | 2013 | 16th |
| Alex Barrientos | C.C. | 2013 | 13th |
| Gene Derricotte | Football | 1943 | U. of Michigan |
| Gene Baldwin | Football | 1953 | Army |
| Jim Hench | Football | 1963 | Ohio Northern |
| Tom Ward | Football | 1997 | U. of Toledo |
| Joe Williamson | Football | 1997 | U. of Toledo |
| Nate Drown | Football | 1998 | - |
| Derek Lynn | Football | 2000 | - |
| Drew Price | Football | 2000 | - |
| Brock Dodrill | Football | 2000 | U. of Toledo |
| Gary Powell | Football | 2000 | - |
| Mark Scott | Football | 2002 | Hillsdale |
| Dan Orta | Football | 2003 | Urbana U. |
| Aaron Swanson | Football | 2009 | - |
| Harry "Red" Miller | Football | - | LT, HB Notre Dame |
| Walter Miller | Football | - | Hb Notre Dame |
| Don Miller | Football | - | One of the four Horseman |
| Dave Preston | Football | - | Bowling Green, D. Broncos |
| Trey Guilliam | Football | 2013 | |
| Mackenzie Peffley | Softball | 1997 | Tri-State |
| Kayla Johnson | Softball | 2006 | University of Findlay |
| Lindsay Tobias | Softball | 2009 | U. of Toledo |
| Brie Hagerty | Volleyball | 2002 | U. of Washington |
| Rachelle Hagerty | Volleyball | 2006 | U. of Minnesota |
| Dave Harrow | Wrestling | 1971 | State Champ |
| Anthony Meir | Wrestling | 1989 | 6th |
| Todd Miller | Wrestling | 1989 | 4th |
| Charlos Marroquin | Wrestling | 1997 | 3rd |
| BJ Miller | Wrestling | 2009 | 7th |
| Terry Wagenhauser | Wrestling | 2009 | 7th |
| BJ Miller | Wrestling | 2010 | 1st |
| Santana Villarreal | Wrestling | 2013 | 8th |
| Sergio Lopez | Soccer | 2002 | - |
| Dylan Mertz | Soccer | 2005 | - |
| Tim Rosenthal | Soccer | 2007 | - |
| Doug Herrett | Soccer | 2011 | - |
| Mike Costello | Tennis | 1966 | - |
| Gary Wagner | T & F | 1952 | 440-4th |
| Jimmy Wandnagle | T & F | 1977 | Mile-2nd |
| Graig Cox | T & F | 1983 | 110HH-4th |
| Kim Hill | T & F | 1987 | High Jump-2nd |
| Martie Wurst | T & F | 1987 | Long Jump-2nd 400-2nd |
| Renee Stahl | T & F | 1988 | Long Jump- State Champs |
| Traci Parsons | T & F | 1990 | 300 Hurdles-5th |
| Traci Parsons | T & F | 1991 | 300 Hurdles-5th |
| Traci Parsons | T & F | 1992 | 300 Hurdles-4th |
| Kyle Kraber | T & F | 1992 | Pole vault-6th |
| Alex Sprague | T & F | 1994 | High Jump-6th |
| Josh Hacker | T & F | 1998 | Discus-6th |
| Josh Hacker | T & F | 1999 | Discus-4th |
| Sarah Mallet | T & F | 2001 | High Jump-2nd |
| Eric Steyer | T & F | 2001 | 800m-7th |
| Patrick Mouser | T & F | 2000 | 3200m-5th |
| Patrick Mouser | T & F | 2001/02 | 3200m-7th |
| Dan Orta | T & F | 2003 | Shot-7th |
| Katy Born | T & F | 2006 | Pole Vault-6th |
| Austin Trivett | T & F | 2007 | Pole Vault-4th |
| Lauren Fett | T & F | 2008 | 1600m-5th |
| Tolbert, Fett, Zipfel, Herret | T & F | 2008 | Girls 4x4 Relay-4th |
| Tolbert, Fett, Volgelsong, Meyer | T & F | 2009 | Girls 4x8 Relay-4th |
| Zach Wiles | T & F | 2009 | 3200m-2nd |
| Brown, Flickenger, Wiles, Murray | T & F | 2009 | Boys 4x8 Relay-1st |
| Megan Vogelsong | T & F | 2010 | 3200 M- 1st place |
| LaKesha Young | T & F | 2011 | Long Jump- 6th place |
| Derron Pritchett | T & F | 2011 | Long Jump- 4th place |
| Sam Murray | T & F | 2011 | 400m-2nd |
| Abel Flores | T & F | 2011 | 3200 M 3rd |
| Abel Flores | T & F | 2013 | 3200 M State Champ |
| Ben Rath | T & F | 2013 | 6th |
| Sam Murray | T & F | 2013 | 800 M-State runner up |
| Sam Murray | T & F | 2014 | 800 M - State Champ |
| Ben Rath | Swimming | 2013 | 500 Free-8th |